(PDF) (DOC) (JPG)June 5, 2012

(MAHWAH, NJ) – Junior Camille Menendez ’13, of Hasbrouck Heights, New Jersey, a Bioinformatics major, co-authored a research manuscript with Associate Professor of Computer Science Scott Frees and Professor of Biology Paramjeet Bagga titled “QGRS-H Predictor: A Web Server for Predicting Homologous Quadruplex Forming G-Rich Sequence motifs in Nucleotide Sequences” for the prestigious international peer reviewed journal, Nucleic Acids Research, published by Oxford University Press.

Nucleic Acids Research publishes leading edge research concerning physical, chemical, biochemical and biological aspects of nucleic acids and proteins in nucleic acid metabolism and/or interactions.  The journal publishes papers concerning in the following fields: Chemistry and synthetic biology; Computational biology; Gene regulation, chromatin and epigenetics; Genome integrity, repair and replication; Genomics; Molecular biology; Nucleic acid enzymes; RNA and Structural biology.

The manuscript discusses the significance of G-quadruplex structures in important biological processes, human disease, and as therapeutic targets. It describes the development, at Ramapo College, of a new bioinformatics computer program, the QGRS-H Predictor, that maps and analyzes evolutionarily conserved G-quadruplex gene regulatory motifs in mRNAs, ncRNAs, and genomic sequences.  The manuscript’s abstract cites the tool as “a unique and user-friendly application that provides many options for defining and studying G-quadruplexes.” The research manuscript was first published online on May 10, 2012.

The article can be freely accessed at: http://nar.oxfordjournals.org/cgi/content/abstract/gks422v1?ct=ct.

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About Ramapo College

Ramapo College of New Jersey is the state’s premier public liberal arts college and is committed to academic excellence through interdisciplinary and experiential learning, and international and intercultural understanding. The comprehensive college is situated among the beautiful Ramapo Mountains, is within commuting distance to New York City, was named one of the 50 Most Beautiful College Campuses in America by CondeNast Traveler, and boasts the best on-campus housing in New Jersey per Niche.com. Established in 1969, Ramapo College offers bachelor’s degrees in the arts, business, data science, humanities, social sciences and the sciences, as well as in professional studies, which include business, education, nursing and social work. In addition, the College offers courses leading to teacher certification at the elementary and secondary levels, and offers graduate programs leading to master’s degrees in Accounting, Applied Mathematics, Business Administration, Contemporary Instructional Design, Computer Science, Creative Music Technology, Data Science, Educational Leadership, Nursing, Social Work and Special Education, as well as a Doctor of Nursing Practice.

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